Cavaliers vs. Pacers Prediction Tonight: Game 4 Odds & Expert Picks

We like the prospect of Cleveland leveling the series at two games apiece as we offer our Cavaliers vs. Pacers prediction for tonight's Game 4.

Brenden Schaeffer

Last updated: May 11, 2025 7:36 AM EDT • 3 min read

Cavaliers vs. Pacers Prediction Tonight: Game 4 Odds & Expert Picks, May 11 — Pictured: Cleveland Cavaliers guard Donovan Mitchell shoots the ball while Indiana Pacers center Myles Turner defends. Photo by Trevor Ruszkowski via Imagn Images

The Cleveland Cavaliers look to make it consecutive wins when they face the Indiana Pacers in tonight's Game 4 from Gainbridge Fieldhouse (8 p.m. ET, TNT) as we offer our Cavaliers vs. Pacers prediction, part of our NBA picks.

Our best sports betting sites have the Cavaliers as 5.5-point betting favorites despite being on the road.

🔢 Cavaliers vs. Pacers updated betting action

Updated betting info via BetMGM.

The Cavaliers moved from 4.5-point (-110) betting favorites to -5.5 (-110)
The total decreased from 231.5 to 230.5
Cleveland moved from -185 to -220 on the moneyline

💰 Cavaliers vs. Pacers expert picks for Game 4

🔎 Our NEW NBA player prop odds tool can help you find the best NBA odds across legal sportsbooks in your area!

✅ Against the spread pick: Cavaliers -4.5 (-115 via BetMGM) ⭐⭐⭐⭐⭐
✅ Moneyline pick: Cavaliers (-190 via BetMGM) ⭐⭐⭐
✅ Over/Under pick: Over 230.5 (-115 via BetMGM) ⭐⭐⭐

🏀 Game 4 prediction & best bet

🎯 Score prediction: Cavaliers 121, Pacers 111

The Cavaliers showed in Game 3 why they were the best road team in the NBA for sports bettors throughout the season. Despite having their backs up against the wall, the top seed in the East cruised to a 22-point win in Indy to improve to 29-15 ATS on the road, easily the best cover rate in the league.

Donovan Mitchell went nuclear in Game 3 as the veteran guard seems determined to reach his first-ever conference finals.

The Pacers awakened a beast. Tyrese Haliburton is far too inconsistent to rely upon as this series tightens; the hero of Game 2 was a ghost in Game 3, scoring just four points. The line for Game 4 moved only a couple of points compared to the Game 3 spread. Cavs -4.5 isn’t enough to keep the Pacers in play against a Cleveland team with a +9.6 average margin in away games.

✅ Best bet: Cavaliers -4.5 (-115 via BetMGM)

Up To $1,500 First Bet

Bonus bets will expire in 7 days. One new customer offer only. Additional terms and conditions apply.

Claim $1,500

Each product featured on our website has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.

📈 Cavaliers vs. Pacers odds

Live updated odds from our best sports betting sites.

🪧 Game 4 opening odds

Opening odds via BetMGM.

Spread: Cavaliers -4.5 (-110) | Pacers -4.5 (-110)
Moneyline: Cavaliers -185 | Pacers +150
Over/Under: Over 231.5 (-110) | Under 231.5 (-110)

🚑 Cavaliers vs. Pacers injury report

Follow the official NBA injury report for more injury news.

📡 How to watch Cavaliers vs. Pacers live (Game 4)

📅 Sunday, May 11
🕗 8 p.m. ET
📍 Gainbridge Fieldhouse (Indianapolis)
📺 TNT | 🛜 Max

💵 Best NBA betting sites

Want to bet on the NBA playoffs? Check out the best NBA betting sites and best sportsbook promos for today's games:

(21+. Gambling Problem? Call 1-800-GAMBLER)
* Bonuses not applicable in Ontario.

Not intended for use in MA.
Each betting site featured on SBR has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.

Written By:
Brenden Schaeffer

Brenden has covered the St. Louis Cardinals as a credentialed baseball writer for KMOV-TV since 2016. His sports writing has appeared in outlets including the Austin American-Statesman and Columbia Daily Tribune. Since 2021, Brenden has co-hosted 'The Big Show' during the afternoon drive for KTGR, the ESPN radio affiliate in Columbia, MO. He has appeared on radio stations around the country, including KMOX, and hosts a daily St. Louis Cardinals podcast. In the sports betting content space, Brenden has covered the NFL, college football, NBA, and college basketball for outlets including SBR since 2019. For his football handicapping, Brenden looks to target NFL player prop markets as well as sharp underdog lines in college football. Brenden looks to reference FanDuel for his sports betting articles because of its consistently competitive odds on parlays. FanDuel's boost offerings are also customer-friendly, and its odds on the NFL Same Game Parlay articles he's written for SBR have historically been consistently competitive compared to other books.