March Madness Odds 2025: Duke Stands Alone as Favorite With Bracket Set

Selection Sunday shook up the March Madness odds as the 2025 NCAA Tournament was set, but Duke remains the clear-cut favorite to win the national championship on Monday, April 7.
Duke, Florida, Auburn, and Houston were awarded the four No. 1 seeds in the 2025 March Madness bracket. As such, it's no surprise to see those same four teams leading the March Madness odds following Selection Sunday. Duke's market-best odds of +350 represent an implied win probability of 22.22% in the 68-team field.
The first round of March Madness begins Thursday, with the four First Four games played Tuesday and Wednesday to set the field of 64.
π 2025 March Madness odds for all 68 teams
The March Madness odds below select the best odds from our best sports betting sites. Throughout the NCAA Tournament, visit Sportsbook Review to get the best college basketball prop bets today.
- Duke: Cooper Flagg is leading the Wooden Award odds, and seemingly avoided an injury scare after he left Thursday's ACC quarterfinal against Georgia Tech; he's expected to be on the court when Duke opens its tournament play on Friday
- Auburn: The Tigers closed the regular season with back-to-back losses to Texas A&M and Alabama, but that didn't stop Auburn from earning a No. 1 seed
- Florida: Closing the season with wins over Texas A&M and Alabama after beating Auburn a few weeks ago helped earn the Gators a No. 1 seed
- Houston: A defensive juggernaut, the Cougars' only loss since early December was to Texas Tech, and they earned their revenge while notching an eight-point win on the road in a rematch
π March Madness odds favorites 2025
π Duke March Madness odds (+350)

Flagg is positioned to potentially become just the fourth true freshman to win the Wooden Award, and he's expected to be the No. 1 pick by the NBA draft odds. That's why Duke was beginning to look like the team to beat before its loss to Clemson.
But the Blue Devils have bounced back in a massive way while recording eight straight 13-plus-point wins to close out the regular season. The biggest flex was when Jon Scheyer's team tallied a 43-point triumph over Illinois at Madison Square Garden, proving that Duke can win a title even with a freshman-heavy lineup.
What makes Scheyer's squad so dangerous is that it's not just Flagg carrying the load, as Kon Knueppel and Tyrese Proctor are two of the top ACC players. In a down year for the conference, Duke is poised to finish strong and make a March run that could lead to a $10 bet paying a $35 profit at BetMGM if the Blue Devils win the NCAA Tournament.
Duke's odds to win the NCAA Tournament settled back to +350 after Flagg seemingly avoided Thursday's injury scare:
Best odds: +350 via BetMGM | Implied probability: 22.22%
π Florida March Madness odds (+425)

It's safe to say that Duke, Auburn, and Houston have been the best teams this campaign while leading a conference for a reason. But after those three it's hard to argue against Florida and Alabama at least being the next two teams nobody wants to play in March because of the offensive prowess being trotted out.
The Gators have really been turning it on over the last month outside of a loss to Georgia, a stretch that includes wins over Auburn, Texas A&M, and Alabama. The foursome of Walter Clayton Jr., Alijah Martin, Alex Condon, and Will Richard will be one of the most lethal in the NCAA Tournament. Earning a No. 1 seed in the NCAA Tournament moved the Gators to second on the March Madness oddsboard.
Best odds: +425 via bet365 | Implied probability: 19.05%
π― Auburn March Madness odds (+500)

The top-ranked offensive team according to KenPom, Auburn survived while Broome was on the mend, and now he's back in full force. Arguably the best two-way player in the country, Broome had Auburn looking unbeatable against Alabama and Kentucky before falling to Texas A&M and the Crimson Tide in a rematch over the final two regular-season games.
While those were two tough losses to stomach, the Tigers were bound to lose a handful of games in an SEC conference many believe to be the toughest ever. With Broome playing dominant basketball, and Auburn featuring five other players scoring in double digits, this is the most battle-tested team in the country.
If the talent around Broome - like Tahaad Pettiford and Chad Baker-Mazara - can continue to complement him and carry Bruce Pearl's team to a title, a $10 winning bet on the Tigers pays a $50 profit at BetRivers.
Best odds: +500 via BetRivers | Implied probability: 16.67%
π My March Madness contender to watch
π Houston March Madness odds (+700)

Houston has been locked in over the last two months after a bit of a slow start. Kelvin Sampson's squad showed it was ready to compete for a title when it went into United Supermarkets Arena and managed a 69-61 win during a rematch against Texas Tech after the Red Raiders beat them on Feb. 1 to end Houston's 13-game winning streak. That came after beating Iowa State, too.
The Cougars are top 10 in both offensive and defensive efficiency, and they boast an eight-deep lineup made up of fierce defenders and versatile scorers. With LJ Cryer and J'Wan Roberts leading the charge, the Cougars hold a shot to win the NCAA Tournament, which would turn a $10 bet into an $70 profit. Houston is clearly the third-best team in the country right now.
Best odds: +700 via BetRivers | Implied probability: 12.50%
π² March Madness odds betting insights: Selection Sunday
Below are betting insights from BetMGM for this year's NCAA Tournament following Selection Sunday.
Highest ticket percentage
- Duke: 13.5%
- Auburn: 7.0%
- Michigan State: 6.9%
Highest handle percentage
- Duke: 23.0%
- Florida: 15.4%
- Auburn: 8.2%
Biggest liabilities
- Duke
- Florida
- Michigan State
Notable bets
- $100,000 on Florida to win March Madness (+900)
- $2,000 on St. John's to win March Madness (+5000)
- $1,000 on Missouri to win March Madness (+12500)
- $400 on Michigan State to win March Madness (+50000)
π March Madness opening odds
March Madness opening odds via FanDuel.
- Duke: +1100
- Kansas: +1100
- UConn: +1200
- Houston: +1400
- North Carolina: +1600
- Kentucky: +1800
- Alabama: +2000
- Arizona: +2000
- Baylor: +2000
- Gonzaga: +2000
- Michigan State: +2500
- Purdue: +2500
- Tennessee: +2500
- Auburn: +3000
- Iowa State: +3000
- Texas: +3000
- Creighton: +3500
- Marquette: +3500
- Arkansas: +4000
π¨οΈ Printable March Madness bracket 2025
You can download a March Madness bracket PDF right here to fill in with your projected NCAA Tournament field.
Auburn, Duke, Houston, and Florida earned the four No. 1 seeds in the South, East, Midwest, and West regions, respectively.
π’ March Madness betting history
Year | Team | Preseason odds |
---|---|---|
2023-24 | UConn | +2000 |
2022-23 | UConn | +8000 |
2021-22 | Kansas | +1400 |
2020-21 | Baylor | +800 |
2019-20 | Canceled | |
2018-19 | Virginia | +1350 |
2017-18 | Villanova | +2700 |
2016-17 | North Carolina | +1900 |
2015-16 | Villanova | +2500 |
2014-15 | Duke | +900 |
2013-14 | Connecticut | +6500 |
2012-13 | Louisville | +700 |
π‘ How to bet on March Madness
First, pick a reputable sportsbook among our best March Madness betting sites. Check out the odds for various teams; for example, if Duke is at +500 and Gonzaga is at +800, Duke is more favored to win. Decide how much you want to wager and place your bet. If you bet $100 on Duke at +500 and they win, youβll get $600 back ($500 profit + $100 stake). Use the March Madness betting promos to get the most out of any wagers on the NCAA Tournament winner.
Now, why do odds move in future markets? It's all about performance and perception. If a team starts performing better or worse than expected, their odds will shift. Injuries to key players can significantly impact a team's chances and their odds. Changes in team dynamics, coaching, or even new player acquisitions can also affect odds. Public betting trends play a role too; if many people are betting on a particular team, sportsbooks might adjust the odds to manage their risk.
Expert analysis and predictions can also sway public opinion and betting patterns. Understanding these factors helps you make smarter bets and potentially catch favorable odds shifts.
βMarch Madness FAQs
Who is the March Madness 2025 favorite?
The Duke Blue Devils are the favorites to win the 2025 NCAA Tournament with +350 odds. Those odds imply a win probability of 22.22%.
Who won March Madness last year?
UConn defeated the Purdue 75-60 to win the 2024 NCAA Tournament. That marked back-to-back victories for the Huskies.
When does March Madness start?
Selection Sunday was Sunday, March 16 with the First Four being played on March 18 and 19. The first round of the NCAA Tournament will then be played March 20 and 21, followed by the second round on March 22 and 23.
The Sweet 16 and Elite Eight are the following week between March 27 and 30. The Final Four is on April 5 with the championship on April 7.
When will March Madness be decided?
The 2025 national championship game will take place on Monday, April 7.
Where will March Madness be played?
The Final Four of the 2025 NCAA Tournament will be played at the Alamodome in San Antonio.
π March Madness betting odds pages
π Best March Madness betting sites
Ready to place your March Madness bets? Check out the best March Madness betting promos from our best March Madness betting sites, as determined by our expert team at Sportsbook Review.
- Caesars Promo Code: SBRBONUSDYW | Read our Caesars Review
- BetMGM Bonus Code: SBRBONUS | Read our BetMGM Review
- bet365 Bonus Code: SBRBONUS | Read our bet365 Review
- FanDuel Promo Code | Read our FanDuel Review
- DraftKings Promo Code | Read our DraftKings Review
(21+. Gambling Problem? Call 1-800-GAMBLER)
* Bonuses not applicable in Ontario.
Not intended for use in MA.
Each betting site featured on SBR has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission