Who Will Score the 1st Touchdown of the 2025 NFL Season? Cowboys vs. Eagles Predictions & Prop Bets

Who will reach the end zone first as the Cowboys and Eagles kick off Week 1 of the NFL season?

Gabe Henderson

Last updated: May 12, 2025 1:30 PM EDT • 3 min read

Who Will Score the 1st Touchdown of the NFL Season? Cowboys vs. Eagles Anytime TD Scorer Predictions — Pictured: Philadelphia Eagles quarterback Jalen Hurts (1) scores a touchdown in the first quarter against the Dallas Cowboys. Photo by Tim Heitman via Imagn Images.

The Dallas Cowboys and Philadelphia Eagles kick off the 2025 NFL regular season with a Week 1 matchup guaranteed to produce fireworks. Our Cowboys vs. Eagles anytime touchdown scorer predictions - part of our NFL picks - highlight key players who could find the end zone early and often in the NFC East clash.

Kickoff is set for Thursday, Sept. 4, at 8:20 p.m. ET (NBC) from Lincoln Financial Field in Philadelphia. Our best sports betting sites list the hosts as 7-point betting favorites with a total set at 46.5. The high total presents opportunities to capitalize on player props - read on for our favorite touchdown scorer predictions.

👉 Check out our Cowboys vs. Eagles prediction and odds for full analysis of the NFL season opener.

🏈 Best Cowboys vs. Eagles anytime touchdown scorer predictions

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✅ Jalen Hurts first touchdown scorer (+500 via DraftKings) ⭐⭐
✅ CeeDee Lamb anytime touchdown scorer (+140 via DraftKings) ⭐⭐⭐

🔥 Jalen Hurts first touchdown scorer ⭐⭐

Hurts only opened the scoring for Philadelphia in four of his 19 appearances last year - two of 15 in the regular season - but one of those instances was against Dallas. The Eagles' star QB torched the Cowboys in his lone appearance against their NFC East rivals last season, totaling four total touchdowns and two with his legs.

It's a crapshoot when trying to predict Philadelphia's first scorer given the amount of weapons on its offense. As such, we'll bank on Dallas attempting to silence Saquon Barkley in the season opener. Hurts could take advantage of that and scramble into the end zone. If he does, a $10 winning wager pays $50 at our best sports betting apps.

✅ Best odds: +500 via DraftKings (bet $10 to win $50 profit)

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🔥 CeeDee Lamb anytime touchdown scorer ⭐⭐⭐

Dallas addressed its mediocre running game in the offseason by adding ... Javonte Williams and Miles Sanders. Cue the world's smallest violin. Those two backs scored a total of seven touchdowns last season, so we're staying far away from betting on any Cowboys ATTS out of the backfield.

Instead, we'll look to Dak Prescott's favorite target. Lamb has found the end zone three times in his last five games against Philadelphia and 38 times across five seasons overall. Given Prescott's track record against the Eagles (24 touchdowns, eight interceptions), we'll take a flyer on Lamb at plus-money.

✅ Best odds: +140 via DraftKings (bet $10 to win $14 profit)

📊 Cowboys vs. Eagles anytime touchdown odds

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Written By:
Gabe Henderson

Gabe Henderson is a sports betting writer from Houston, Texas. He graduated from Louisiana State University in 2022 with a bachelor's degree in Mass Communication. Gabe developed an interest in sports betting while in college due to its legalization in Louisiana. He turned his passion into a career shortly after, joining The Advocate/NOLA.com as a Sports Betting Content Coordinator, where he spent two years. Gabe wore many hats before graduating as he led FanSided's coverage of Chelsea FC as a Site Expert with "The Pride of London." He was also the Editor-in-Chief of the LSU Gumbo Yearbook for two years. Gabe became a part of the SportsbookReview.com team in late 2024. He brings with him an extensive knowledge of many sports, including — but not limited to — NFL, NCAA, MLB, NBA, soccer, and UFC.