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March Madness Final Four Odds & Schedule
Pictured: Duke Blue Devils forward Cooper Flagg drives to the basket against Alabama Crimson Tide guard Mark Sears. Photo by Robert Deutsch via Imagn Images

Four No. 1 seeds have advanced to the Final Four of March Madness for the first time in 17 years with Auburn, Duke, Houston, and Florida vying for the national championship. 

The Duke Blue Devils have been the most impressive team during the NCAA Tournament, which their March Madness odds reflect. Let's look at the 2025 March Madness Final Four schedule and odds, with mouthwatering battles to determine the finalists set for Saturday. 

🗓️ March Madness Final Four schedule

Here is the March Madness Final Four schedule. Listed odds are from BetMGM.

DayMatchupTimeHow to watch
SaturdayNo. 1 Florida vs. No. 1 Auburn6:09 p.m. ET CBS
SaturdayNo. 1 Duke vs. No. 1 Houston 8:49 p.m. ETCBS

🏀 Final Four odds 

No. 1 Florida vs. No. 1 Auburn odds, 6:09 p.m. ET

  • When: Saturday, April 5 | 6:09 p.m. ET
  • Where: Alamodome (San Antonio)
  • How to watch: CBS

👉 See all of the college basketball odds from our best March Madness betting sites.

No. 1 Duke vs. No. 1 Houston odds, 8:49 p.m. ET

  • When: Saturday, April 5 | 8:49 p.m. ET
  • Where: Alamodome (San Antonio)
  • How to watch: CBS

⏰ When is March Madness Final Four?

The 2025 NCAA Tournament Final Four takes place on Saturday, April 5. The early game featuring Florida and Auburn starts at 6:09 p.m. ET, and tipoff for the later game between Duke and Houston is at 8:49 p.m. ET. 

🧠 Final Four expert picks

💰 March Madness betting odds pages

👑 Best March Madness betting sites

Ready to place your March Madness bets? Check out the best March Madness betting promos from the best March Madness betting sites, as determined by our expert team at Sportsbook Review.

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