Updated March Madness Bracket & Second Round Matchups: NCAA Tournament Odds & Predictions

The 2025 NCAA Tournament is off and running, and things have gone mostly according to plan through one day of action across the country. Unless, of course, you're a fan of the Clemson Tigers, Missouri Tigers, Kansas Jayhawks, or Louisville Cardinals.
Those were the four programs to be upset on Day 1. We've updated our March Madness bracket to reflect those changes heading into the second round, with the McNeese Cowboys, Drake Bulldogs, Arkansas Razorbacks, and Creighton Bluejays advancing.
Here is our updated March Madness bracket entering Friday's play, with Saturday's eight matchups set.
Updated March Madness bracket
We have you covered for Friday and Saturday's games with our college basketball picks.

Saturday's second-round matchups
Here are the second-round matchups for Saturday after Thursday's games:
- (12) McNeese vs. (4) Purdue, Midwest Region: 12:10 p.m. ET (CBS)
- (10) Arkansas vs. (2) St. John's, West Region: 2:40 p.m. ET (CBS)
- (5) Michigan vs. (4) Texas A&M, South Region: 5:15 p.m. ET(CBS)
- (11) Drake vs. (3) Texas Tech, West Region: 6:10 p.m. ET (TNT)
- (9) Creighton vs. (1) Auburn, South Region: 7:10 p.m. ET (TBS)
- (6) BYU vs. (3) Wisconsin, East Region, 7:45 p.m. ET (CBS)
- (8) Gonzaga vs. (1) Houston, Midwest Region: 8:40 p.m. ET (TNT)
- (7) UCLA vs. (2) Tennessee, Midwest Region: 9:40 p.m. ET (TBS)
Updated March Madness odds
Here's a look at the live March Madness odds from our best March Madness betting sites with the first eight teams eliminated. These odds will update in real time.
Second round March Madness odds
Here are the odds for Saturday's eight NCAA Tournament games, with play beginning at 12:10 p.m. ET.
Purdue vs. McNeese odds, 12:10 p.m. ET
π See Brenden Schaeffer's Purdue vs. McNeese prediction.
St. John's vs. Arkansas odds, 2:40 p.m. ET
π See Isaiah Sirois' St. John's vs. Arkansas prediction.
Texas A&M vs. Michigan odds, 5:15 p.m. ET
π See Philip Wood's Texas A&M vs. Michigan prediction.
Texas Tech vs. Drake odds, 6:10 p.m. ET
π See Isaiah Sirois' Texas Tech vs. Drake prediction.
Auburn vs. Creighton odds, 7:10 p.m. ET
π See Philip Wood's Auburn vs. Creighton prediction.
Wisconsin vs. BYU odds, 7:45 p.m. ET
π See Mike Spector's Wisconsin vs. BYU prediction.
Houston vs. Gonzaga odds, 8:40 p.m. ET
π See Brenden Schaeffer's Houston vs. Gonzaga prediction.
Tennessee vs. UCLA odds, 9:40 p.m. ET
π See Brenden Schaeffer's Tennessee vs. UCLA prediction.
π° March Madness betting odds pages
March Madness odds | March Madness MVP odds |
Women's March Madness odds | March Madness MVP predictions |
Final Four odds | March Madness prop bets |
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